Brainpeps Help

Brainpeps®

Help

The Brainpeps® website gives an overview of peptides for which blood-brain barrier transport data are available and describes their chemical and functional properties.
On this help page, we will help you navigate through the database content. Dragging your mouse cursor on the - symbol gives you specific information related to that part of the database.

Home page

At the home page of Brainpeps®, a search box is given. In this box, you can enter your keyword: peptide name, abbreviation of the peptide name, peptide sequence (IUPAC one- or three-letter amino acid code), molecular formula (using the CxHxNxOxSxClx format), method name, response name and literature information (author [or] title [or] journal name (full) [or] year). If your initial search does not return results, try a different synonym.

Search criteria Example
Peptide name Endomorphin-1
Peptide sequence YPWF or Phe-Pro-Trp-Phe
Molecular formula C34H38N6O5
Method Intravenous injection MTR
Response Kin
Author Banks
Article title Differential Transport of a Secretin Analog across the Blood-Brain and Blood-Cerebrospinal Fluid Barriers of the Mouse
Journal name (full) The Journal of Pharmacology and Experimental Therapeutics
Year 2002

If you want to browse the database content, press the search botton without any keyword filled in the search field.

When searching for a specific method or response name, a list of all possible entries can be obtained when hovering the mouse cursor over the - symbol next to the specific criteria. You can easily click on a specific word from the drop-down box to obtain a list of all peptides related to that criterion.

At the home page of Brainpeps®, you have the opportunity to submit new information by clicking Data submission to Brainpeps. After filling in the form, we will put your information into the Brainpeps® database. Our detailed contact information can be found after clicking Contact us; the schematic database model is obtained after clicking Database model.

Access to the home page can be obtained by pressing Home at the top of every page.

Result page

After clicking the search button, a structured overview of the results is given. The first column of the results table gives the ID-numbers of the different peptides. If you wish to see more detailed information regarding a specific peptide, please click its ID-number (see Molecule page). The last column gives the reference-ID, in which the specific peptide is described. If you wish to see more details regarding a related publication, please click its ID-number (see Publication page).

Molecule page

After clicking the ID-number of a specific peptide, all detailed information regarding that peptide is obtained. At the top of this page, the structure of the selected peptide is shown; this .hin structure file can be downloaded to your computer. The structure can also be rotated by dragging the structure; zooming is possible by scrolling on it.

Next to the structure, detailed information about the chemical and functional properties, origin and literature is given. All this information is shown after clicking the right symbol of the selected title box.

Publication page

After clicking the ID-number of a specific reference, all detailed information regarding this publication is shown. The article itself can be downloaded after clicking the Download link.